Behind its classic exterior of intricate wrought-iron balconies lies a truly eclectic, almost cinematic milieu. Its owners hired a team of high-profile architects and designers to create an irreverent yet carefully curated atmosphere. Alma Histórica, Montevideo Italian financier and art collector Gianfranco Bonan was so captivated by Uruguay that he bought a summer home on the beach and then built a boutique hotel (pictured at top) in Montevideo’s Old City, or Ciudad Vieja.

 Fall is a prime time to travel, especially with chic new hotels opening around the globe.com.com/product/jar-preform-mould/">Wholesale Jar Preform Mould plaza in the neighborhood. Some of the 17 airy rooms face an interior garden planted with palm trees and jasmines; all have plush beds and modern bathrooms. This elegant property pays tribute to local culture; its 15 rooms and suites are dedicated to Uruguayan icons like the poet Juana de Ibarbourou (her room is decorated in soft lilac tones and filled with feminine ornaments like antique hand-held mirrors) and the painter Joaquín Torres García (whose suite has clean lines and bright colors that emulate the artist’s constructivist style). Every floor has hallways painted in dramatic colors—deep blue or fiery red, for example—leading to polished rooms featuring leather headboards and granite-topped nightstands. In addition to looking stylish, they’ll be happy to tell you about the latest openings or suggest off-the-beaten-track experiences. Just steps away are the boutiques and cafes of Santiago’s Barrio Brasil, a historic neighborhood in the midst of a revival. Staffers wear denim shirts and graphic pants from local retailer Basico. Rooms have exposed electrical wiring, cement floors and photographs from Compota Edições Limitada, an artist collective. This three-story building from 1912 underwent lengthy renovations that brought fresh luster to its turn-of-the-century facade, parquet flooring, and intricate ceiling Pet Mould Manufacturers moldings.

Matildas Hotel Boutique, Santiago Classic French architecture and beautifully designed interiors made Matildas Hotel Boutique an instant favorite among clued-in travelers when it opened last April. These intimate new hotels provide a perfect base from which to explore some of the top destinations in the Southern Hemisphere, from Chile to Brazil. Louis XV sofas upholstered in moss-green velvet and herringbone parquet flooring are matched with massive industrial-style doors; the elevator is covered in tufted leather and murals depicting famous Argentinian actresses. Inside, architect Marcelo Varetto mixed chesterfield sofas with crystal chandeliers and trompe l’oeil bookshelves, adding strategically placed contemporary details like brightly colored accent chairs and throw pillows in geometric prints.tzhdmj. Another inviting corner at Alma Historica is the sixth-floor rooftop, which faces the most romantic